"Nanogen is an
invaluable addition
in the fight against
hair loss..." Dr Rogers - Rogers Medical
More
Re-Growth
than Minoxidil*
*When tested against Minoxidil 2%
Nanogaine ®
Don't Forget...
Nanogaine 2 x 50ml vials
1 month supply
Proven hair
Re-Growth with NO
Nanogaine is proven to re-grow more hair than Minoxidil®,
by blocking the NO - Peroxynitrite pathway. Water soluble
to avoid drying the hair and scalp.
In a controlled test of Nanogaine, hair growth response was observed in 6 out of 6
cases after 14 days, and hair growth rate was 90%. In comparison Minoxidil 2%
(Rogaine, Upjohn) showed hair growth response for 5 out the 6 cases in 28 days
and hair growth rate was at 57%
What
is Nanogaine?
Nanogaine is a hair loss treatment that has been shown
to:
Help to ward off hair loss by inhibiting Free Radicals
and Sebum output
Stimulate hair growth by expanding the Anagen (growth) phase
and shortening the Telogen (resting) phase of the hair
Reduce inflammation in the hair follicle
Long-term Use
It is a fact of any hair re-growth product, whether topical or
oral, that it's
application must be ongoing to maintain results.
Both Minoxidil and Nanogaine work by releasing the Nobel Prize-winning
Nitric Oxide molecule (NO), which acts as a chemical messenger
to the hair follicles. In fact, that is what the NO stands for
in Minoxidil and Nanogen. Minoxidil
is unfortunately only soluble in alcohol solutions and consequently
causes incredibly dry and flaky scalp over long-term use. Furthermore,
this drying effect damages the hair follicle.
Nanogaine represents a breakthrough in hair re-growth technology
as its
formulation is water soluble and thus can be used for years
without any reported adverse effects. With Nanogaine, you get
all the benefits of Nitric Oxide, without the downsides of an
alcohol-based product.
The life
cycle of a hair
In a normal scalp, approximately 90% of hairs are in the Anagen
phase and 10% in either the Catagen or Telogen phase. In cases
of Alopecia, the number of hairs in the Anagen phase drops, while
the number of hairs falling out (Telogen phase) rises.
Clinical trials show that Nanogaine can increase the number of
hairs in the Anagen phase by +15%, at the same time decreasing
the number of hairs in the Telogen phase.
Re-grow your hair with Nanogaine
The Nitric Oxide (NO) pathway
exists within every hair cell. Increased presence of intracellular
Nitric Oxide has been shown to increase the size and section of
the hair follicle (left)
Conversely, Peroxynitrite has been shown to be detrimental to
the health of the hair follicle.
Superoxide Dismutase (SOD) therefore has a double hair growth
stimulation effect - more NO and less Peroxynitrite.
Without Nanogaine:
Nitric Oxide (NO) occurs naturally in the
scalp and is essential for healthy hair growth.
Free Radicals are ever-present in
the scalp and cause
cell damage.
Peroxynitrite is formed when a reaction occurs between
NO and free radicals. Peroxynitrite has been shown to be detrimental
to the health of the hair follicle.
Superoxide Dismutase (SOD) is a naturally occurring enzyme, present in every cell and specialising in the quenching
of large volumes of the free radicals which attach to Nitric
Oxide.
How Nanogaine Works:
Nanogaine contains the
bio-mimetic form of SOD which is present in high concentration
to boost the natural free radical scavengers within every
hair cell.
What else does Nanogaine contain other than patented 'bacterial filtrate SOD peptides'?
Capilecti ™ has been shown to expand the
Anagen (growth) phase and shorten the Telogen (resting) phase
by 17%. Capilecti is a lectin-like glycoprotein helping to
agglutinate hair follicle cells together.
Lo-Seb ™ is a complex of homotaurine, bacterial
filtrate peptides and marine derived sulphomucopolysaccharide extract.
Lo-Seb reduces sebum output by 16% and is effective in normalizing
Seborra often implicated in alopecia. Lo-Seb also has been shown
to increase the percentage of hair in the Anagen (growth) phase
by 15% (from 74.6% to 85.5%)
Nanogaine increases the size of the hair follicle, expanding
the Anagen phase and shortening the Telogen phase.
These microscope photographs demonstrate the 'lectin-like' effect
Nanogaine
has on the cells, that is, it contains a glycoprotein
that agglutinates
(clumps together) the hair follicle cells, assisting
hair growth.
Clinical Research behind Nanogaine
Topical
application test
The hair of the lumbar region (small 5cm patch) of six C3H mice
was cut and 0.1ml of SOD extract was applied twice a day, until
hair growth was observed. The area of hair growth was monitored
with an image analyzing apparatus
on days 14, 21 and 28 following the start of the test.
At 1% concentration of SOD, hair growth response was observed
in all cases after 14 days and hair growth rate was observed in
all areas of treatment. At 0.5% concentration, hair growth response
was observed in all cases
and hair growth rate was 90%. In comparison, Minoxidil (2% Rogaine,
Upjohn) showed hair growth response
for 5 out of the 6 animals in 28 days and hair growth rate was
at 57%
In Vitro test
It has been shown that Minoxidil increases the DNA synthesis
of skin hair follicle and the synthesis of keratin in the hair
follicle (Buhl AE et al., J Invest Dermatol 1991 May; 96(5):73S-74S)
so it was decided to use the same test for Superoxide Dismutase
for a fair comparison. Addition of only 5-10 µm of SOD extract
provoked hair follicle protein synthesis which was 100-200% higher
than that of Minoxidil (2%)
We are aware that Minoxidil is usually used at 5% concentration
or higher. Nanogaine is formulated with 2% SOD in addition to its other actives such as Lo-Seb™ and Capilecti™. Nanogaine
can be used concurrently with Minoxidil therapy.
A simple search on the Google engine "SOD + Hair loss"
will provide multiple references to the other respected sources
who have tested SOD for applications in hair loss therapy. Indeed
there have been expensive patent fights over this particular ingredient.
Here is a quote from the respected
website Hairlosstalk which we are comfortable quoting
as they do NOT stock Nanogaine:
"SOD's - Also known as Super Oxide Dismutase, these
hair loss treatments work by handling the immune response which
occurs as a result of excessive DHT in the follicle. When cells
sense a foreign body, they release Super Oxide, which typically
help defend the body against invading viruses, cells, and foreign
tissues. SOD's reduce the presence of this Super Oxide, thus reducing
the body's desire to reject the follicle. It's yet another "angle"
proven to work in fighting hair loss. SOD's are kind of a hybrid
treatment because they also have growth stimulation properties,
as well as anti-inflammatory properties."
Frequently
Asked Questions
How long will a pack of Nanogaine
last?
Each pack of Nanogaine is designed to last
1 month of application.
How do I apply Nanogaine, and at
what times are optimal?
Full details on how to apply are printed on
the carton.
When should I expect to see results?
The time taken to see result varies between
individual and for some, little results are achieved.
It would be the same for users of Minoxidil. Some people respond
excellently and others do not respond at all. However in all
cases, users would be advised to allow at least 3 months of
application in order to assess results.
Do I need to use Nanogaine forever?
Yes. Every
clinically proven hair loss treatment without exception
must be used indefinitely. For most people this is not as
daunting as it first sounds, especially with Nanogaine for
several reasons.
First off, Nanogaine is water-based, so unlike Minoxidil, it
does not dry the hair and scalp even with long-term use. Secondly,
not being a tablet whose effects are systemic, it does not have
side effects.
Besides, a lot of people just want to extend the life of
their hair for a further 10 years or just slow down the
loss, so you don't have to use it forever, just if you want
to maintain result you will do.
Applying Nanogaine takes less time that putting in your contact
lenses, just 5 minutes or less.
Are there any side effects from
using Nanogaine?
This is the greatest feature of Nanogaine.
Unlike Minoxidil, which must be dissolved in ethanol (alcohol),
the Nanogaine actives are water-soluble. This was our breakthrough.
This means that you can get all the benefit from 'topical NO
supplementation' without drying the hair. It is a very important
factor when one remembers that Minoxidil must be used for the
rest of your life, or hair re-grown/stopped from falling out,
will then fall out. Nanogaine is a long-term choice for people
who want to have hair and have it healthy looking/feeling too.
Can you use Nanogaine alongside Minoxidil?
Yes you can. Naturally,
there will be some drying because of the alcohol in the
minoxidil solution. Some people use Nanogaine day and night
and use Minoxidil once a day also. You may like to use an
oily hair gel or cream such a "brylcream" to avoid
the worst 'straw-hair' from long-term Minoxidil use.
What if I use the night ampoule in
the day (or vice-versa) what are the effects?
No adverse affects at all. It is just that
at night, your scalp will produce more sebum and the night formula
is designed to slow sebum production and hence the optimum conditions
will be obtained by using the ampoules in the correct order.
What is shedding?
When hair growth is stimulated, a large amount
of follicles move into the Anagen phase from the Telogen phase
simultaneously, which has the obvious consequence of hairloss
during the initial phase of treatment (shedding). Do not be
concerned. Although it may sound counter-intuitive, more than
usual hairloss is usually an indication the formula is working
according to the published studies. The new hair that replaces
that just lost will be thicker, stronger and with more color.
THE INFORMATION ON THIS SITE IS INTENDED FOR A U.S. AUDIENCE
Nanogen provide hair loss treatment & camouflage for thinning hair. Nanofibres is the instant hair thickening hair camouflage with patented technology.
Perfect for both Male and Female hair loss. Only Nanogen hair loss products are approved by the Alopecia Society and recommended by many of the
world's leading hair loss professionals including eminent hair transplant surgeons.
These statement have not been evaluated by the Food and Drug Administration. These products are not intended to diagnose, treat, cure, or prevent any disease.
